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The Clinical Impact of Adverse Event Reporting

Underreporting

Another major concern with any spontaneous reporting system is underreporting of adverse events (16, 30-32). It has been estimated that rarely more than 10% of serious ADRs, and 2-4% of non-serious reactions, are reported to the British spontaneous reporting program (30). A similar estimate is that the FDA receives by direct report less than 1% of suspected serious ADRs(32). This means that cases spontaneously reported to any surveillance program, which comprise the numerator, generally represent only a small portion of the number that have actually occurred. The effect of underreporting can be somewhat lessened if submitted reports, irrespective of number, are of high quality.

http://www.fda.gov/medwatch/articles/medcont/postrep.htm

 

Posted in Health and wellness | 15 Comments

Probable Mechanism of DPT vaccine induced neurological damage

http://www.kem.edu/dept/clinical_pharmacology/adverse_event_month_case/case_june2005.htm

Probable Mechanism of DPT vaccine induced neurological damage:

In implicating pertussis vaccination in the evolution of subsequent neurological residua, a careful consideration of the mechanism for vaccine-induced brain damage plays an important supporting role. Pertussis toxin has been shown to alter cellular signaling. It also affects the catecholaminergic and GABAergic systems in the brain. In addition, a direct, endotoxin-mediated attack on the endothelial cells could create a local defect of the blood-brain barrier. It is being seen that a combination of one or more bacterial toxins, asphyxia, Co2 retention and loss of cerebral autoregulation is responsible for neurological symptoms.

Encephalopathy manifests with alteration of sensorium or generalized or focal seizures that persist for more than a few hours. Occurrence of hypotensive-hyporesponsive shock or post-vaccination encephalopathy is a contra-indication of further doses of the pertussis component. This should be explained to the guardians. Other manifestations that indicate occurrence of encephalopathy include: seizures with or without fever occurring within 3 days of immunization and persistent, severe, inconsolable screaming or crying for 3 or more hours within 48 hours of immunization. Usually, these are not associated with permanent sequel. Previously, occurrence of these events also meant withdrawal of pertussis component from doses to be received in future. However, it is now recommended that all factors should be considered while advising regarding DPT vaccination in future in these children.

Association of severe reactions made the whole- cell pertussis vaccine highly unpopular among many communities and countries and spurred research for safer vaccines. Some European countries even went to the extent of withdrawing (whole-cell) pertussis vaccination; only to find an increased incidence of and increased morbidity due to pertussis amongst infants and young children in the community. An acellular pertussis vaccine (Designated as aP) is now available in several countries including India. It contains purified, inactivated components of B. pertussis. The acellular vaccine is as potent as the whole cell vaccine, but it is still associated with neurological complications described with whole-cell vaccine, albeit at a much lower frequency. It is also credited with lesser incidence of local side effects as well as decreased incidence of severe reactions like seizures and hypotensive episodes. However, the vaccine is expensive and it is unlikely that it would be included in the Indian National immunization schedule in near future.

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Posted in Health and wellness | 4 Comments

But What’s In That Shot Dr?

How I became aware of the vaccine controversy,
 

When my parents were young, they received one dose of one vaccine, smallpox.

When I was young, I received approx 9 doses of 5 vaccines,

Diphtheria

Polio

Tetanus

Smallpox

Pertussis

When my first child was born in 1984, she received approx 21 doses of 7 vaccines,

Diphtheria

Polio

Tetanus

Pertussis

Measles

Mumps

Rubella

When my 3rd child was born in 1995, another new vaccine was added to the schedule, Hib…and he was getting approx 21 doses by the age of 18 months, (the same amount it took my first two children 5 years to accumulate!) with several more doses to go (they added a 2nd dose of the MMR)

Today’s child is expected to get up to 40 plus doses of up to 13 vaccines (if Hep A & influenza are included) and look for ANOTHER dose of varicella to be added, along with other new vaccines in the works.  Currently being injected in today’s children:

Diphtheria

Polio

Tetanus

Pertussis

Measles

Mumps

Rubella

Hep B

Hib

Varicella (chickenpox)

PCV (prevnar)

Hep A

Influenza

The growing number of required vaccines concerned me. Why all these new vaccines when I and my parents and my older two children did just fine without them?  The last straw for me was the Rotashield vaccine that was licensed in August  1998 but less than a year later, in  July of 1999, the CDC recommended that use of the rotavirus vaccine be temporarily suspended due to concerns about bowel obstruction it caused in many infants (intussusception), many needing surgery to correct, and at least 3 infants died.  By October of 1999, the vaccine was "voluntarily" withdrawn from the market by the manufacturer.  One thing led to another, and the end result is a list of resources I have saved, some of which I have used in making my own vaccination decisions.

 

Optimization of vaccine responses in early life: the role of delivery systems and immunomodulators.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9682966&dopt=Abstract

Supporting Children’s Health
by Philip Incao, M.D.

http://www.goodlight.net/vacexpert/suportng.htm

This expert has also stated that in his experience of treating vaxed and unvaxed children, (for over 20 years) the unvaxed are healthier.

Virus-induced autoimmunity may play a causal role in autism

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12849883&dopt=Abstract

Personally, I think a lot of the autoimmune problems our children are suffering from today are vaccine induced.

Puzzling associations between childhood infections and the later occurrence of asthma and

There are data to suggest that measles, hepatitis A, and Mycobacterium tuberculosis infection in early life may prevent the subsequent development of atopic diseases.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11028687&dopt=Abstract

Unlike hepatitis B and hepatitis C, hepatitis A causes no long-term liver damage and usually does not cause death. There is no chronic carrier state with hepatitis A. Having had the disease produces lifelong immunity from future hepatitis A infection.

http://www.hepatitisresources-calif.org/hepa/

Increased susceptibility to measles in infants in the United States.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10545585&dopt=Abstract

Hepatitis B virus transmission between children in day care.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2626287&dopt=Abstract

Duration of hepatitis B immunity in low risk children receiving hepatitis B vaccinations from birth.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15247604&dopt=Abstract

How safe is the Hep B vaccine?

http://www.chop.edu/consumer/jsp/division/generic.jsp?id=75700

Pertussis resurgence in Canada largely caused by a cohort effect.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12544404&dopt=Abstract

VACCINE EXCIPIENT & MEDIA SUMMARY

 

http://www.cdc.gov/nip/publications/pink/Appendices/A/Excipient.pdf

Comparison of tissue reactions produced by Haemophilus pleuropneumoniae vaccines made with six different adjuvants in swine.


http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=4016580&dopt=Abstract

Based on the growing number of children allergic to peanuts, I tried to find out if any type of peanut oil was used in the vaccines. From what I could find, it may be used in vaccines for animals, but I have not yet found conclusive evidence that it’s used in vaccines for people. This is something I am still interested in getting to the bottom of.

Task Force on Safer Childhood Vaccines: Final Report and Recommendations

http://www.niaid.nih.gov/publications/Vaccine/safervacc.htm

Because the PDR was originally developed as a promotional device, there is no mechanism by which all clinically relevant dose-response data or important postrelease discoveries are regularly and rapidly incorporated into it.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11295958&dopt=Abstract

Epidemiology. 1997 Nov;8(6):678-80
Is infant immunization a risk factor for childhood asthma or allergy?

Kemp T, Pearce N, Fitzharris P, Crane J, Fergusson D, St George I, Wickens K, Beasley R.

Department of Medicine, Wellington School of Medicine, New Zealand.

The Christchurch Health and Development Study comprises 1,265 children born in 1977. The 23 children who received no diphtheria/pertussis/tetanus (DPT) and polio immunizations had no recorded asthma episodes or consultations for asthma or other allergic illness before age 10 years; in the immunized children, 23.1% had asthma episodes, 22.5% asthma consultations, and 30.0% consultations for other allergic illness. Similar differences were observed at ages 5 and 16 years. These findings do not appear to be due to differential use of health services (although this possibility cannot be excluded) or con-founding by ethnicity, socioeconomic status, parental atopy, or parental smoking.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9345669&dopt=Abstract

Burton Press Release Expertly Misleads Both The Press And The Public


by Rich Greenaway

On May 1, 2003 a press release originating from the office of Congressman Dan Burton (R-IN) indicated that he would join a panel of scientists, medical researchers, and parents who were convening from across the nation in Chicago, IL to present evidence from recently or soon-to-be released studies linking autism with the mercury-based preservative thimerosal. Part of the premise for Representative Burton’s press release was his statement that the 2003 Physicians Desk Reference (PDR) showed that there are three vaccine manufacturers who are still making childhood vaccines with full doses {his term} of thimerosal. Specifically, his press release of May 1, 2003 stated:

“The 2003 Physicians’ Desk Reference shows that there are three vaccine manufacturers who are still making childhood vaccines with full doses of thimerosal. These are as follows: the Diphtheria-Tetanus-acellular-Pertussis (DTaP) manufactured by Aventis-Pasteur in multi-dose vials contains 25 micrograms of mercury; the Haemophilus-influenza-Type b (Hib TITER) in multi-dose vials manufactured by Wyeth contains 25 micrograms of mercury; and the pediatric hepatitis B vaccine manufactured by Merck contains 12.5 micrograms of mercury. These vaccines represent approximately half of the childhood vaccines currently available for use in the United States.”

After reading the press release, ECBT immediately went into full research mode to find out if Burton’s information was true. Were thimerosal-containing childhood vaccines still listed in the 2003 PDR and did that mean that they were still available in the marketplace? We found out that only one truth was contained in the above quote from Congressman Burton’s press release. That one and only truth is that the above mentioned thimerosal-containing formulations of the childhood vaccines are still listed in the 2003 PDR. The fallacies or misleading points in his statement are “that there are three vaccine manufacturers who are still making childhood vaccines with full doses of thimerosal”; that “these {thimerosal-containing} vaccines represent approximately half of the childhood vaccines currently available for use in the United States.” The reality is that the thimerosal-containing formulations of those vaccines listed in Burton’s press release are no longer in manufacture or distribution in the United States and haven’t been for years. Nor are they available for use in the United States.

In an effort to better understand how a vaccine could be listed in the most current PDR showing that it contains thimerosal when it is no longer manufactured as such, we contacted PDR directly and asked how the information in their reference books is kept current.

The PDR is published yearly by Thomson Healthcare in Montvale, NJ. Manufacturers pay to have their products listed in the PDR and a free copy of the PDR is distributed to office-based physicians. Not all medical products are found in the PDR because a manufacturer may decide for whatever reason not to list a product. Product information found in the PDR comes directly from the manufacturer and is identical to the latest package labeling as approved by the FDA for that product. No changes to content are made by PDR. PDR may reformat the layout of the information but final formatting and content is approved by the manufacturer before PDR goes to print to insure that PDR’s reformatting does not change the content from the original.

Manufacturers have flexibility to make changes to the information on their product in the PDR without submission of those changes to FDA if the new information is considered a “negative” change. Negative changes include new warnings about their product, or new findings that would reflect negatively on its use. Changes of information that would be considered “positive” include information that would further promote or serve to increase use of the product and those changes must be submitted through FDA for approval before they can be inserted into the next PDR edition.

Manufacturers can decide at any time to discontinue production, however, once a manufacturer makes such a decision it is not uncommon for them to keep the information in the PDR for at least a couple of years. The reasons for doing this are varied. Having unexpired product still available in the market, or a recommendation from legal council that a product listing be maintained are but two of the many potential reasons why essentially outdated information may still be maintained in the PDR.

In the case involving this press release, three vaccine manufacturers sited by Burton decided to continue to list descriptions of products in the PDR that they have removed from the U.S. market. ECBT is not privileged to know their reasoning for doing this. We just hope that in the future, Congressman Burton will first investigate further before using misleading information like this as such a major focal point in his press release.

http://www.ecbt.org/0603textonly.html

Pediatric Neurologist comments on Vaccine Reactions"

http://www.eaglefoundation.net/Kinsbourne.htm

I believe this info came from one of the congressional hearings.

CONGRESSIONAL HEARINGS:

FACA: CONFLICTS OF INTEREST AND VACCINE DEVELOPMENT–PRESERVING THE INTEGRITY OF THE PROCESS

http://frwebgate.access.gpo.gov/cgi-bin/getdoc.cgi?dbname=106_house_hearings&docid=f:73042.wais

Mr. Cummings. Have there been any published peer review studies that show a link between hepatitis B vaccine and conditions such as multiple sclerosis and SIDS? Dr. Orenstein. There have been case reports that have suggested that this is a possibility, and that’s why we are doing more comprehensive research. The people who are developing these illnesses after vaccination have very, very severe illnesses; there’s no question that these are terrible tragedies. The problem is that there are people who develop these same kinds of tragedies, these same kinds of illnesses in the absence of vaccination. And that’s why we’re engaged, we and others are engaged in substantial research to try and see whether the vaccine increases the risk over what would be expected.

Scroll down to almost the bottom of the page & look for these statements:

STATEMENTS OF RONALD C. KENNEDY, PROFESSOR, DEPARTMENT OF MICROBIOLOGY AND IMMUNOLOGY, UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER; SAMUEL L. KATZ, PROFESSOR EMERITUS, DEPARTMENT OF PEDIATRICS, DUKE UNIVERSITY MEDICAL CENTER; AND MARCEL KINSBOURNE, PEDIATRIC NEUROLOGIST

HEPATITIS B VACCINE: HELPING OR HURTING PUBLIC HEALTH?

http://frwebgate.access.gpo.gov/cgi-bin/getdoc.cgi?dbname=106_house_hearings&docid=f:63308.wais

MERCURY IN MEDICINE–ARE WE TAKING UNNECESSARY RISKS?

http://frwebgate.access.gpo.gov/cgi-bin/getdoc.cgi?dbname=106_house_hearings&docid=f:72722.wais

VACCINES–FINDING THE BALANCE BETWEEN PUBLIC SAFETY AND PERSONAL CHOICE

http://frwebgate.access.gpo.gov/cgi-bin/getdoc.cgi?dbname=106_house_hearings&docid=f:62560.wais

COMPENSATING VACCINE INJURIES: ARE REFORMS NEEDED?

http://frwebgate.access.gpo.gov/cgi-bin/getdoc.cgi?dbname=106_house_hearings&docid=f:66079.wais

Trends in Deaths Caused by Infectious Diseases in the United States, 1900–1994

http://www.cdc.gov/ncidod/emergplan/box01.htm

You can look up VICP cases here:

http://www.uscfc.uscourts.gov/osm.htm

Wonder why the respondent’s want to keep info under wraps if they don’t have anything to hide.

http://www.uscfc.uscourts.gov/OSM/Autism/6%2023%2004%20Autism%20Update.pdf

Workshop on neurologic complications of pertussis and pertussis vaccination.

1. Vaccines are not standardized between manufacturers.

2. For a given manufacturer, vaccines are not standard from one batch to the next.

3. Unless the vaccine is properly prepared and refrigerated, its potency and reactivity varies with shelf life.

In fact, the whole question of vaccine detoxification has never been systematically investigated.

Listed in order of increasing severity, observed adverse reactions include irritability, persistent, unusually high pitched crying, somnolence, seizures, a shock-like "hypotensive, hyporesponsive" state, and an encephalopathy. Since the neurologic picture is not specific for pertussis vaccination, its temporal relationship to the vaccination is the critical variable for determining causation. Although the majority of seizures following pertussis vaccination are associated with fever, it was the consensus of the neurologists attending the workshop, that these do not represent febrile convulsions, but are non-benign convulsions.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1981251&dopt=Abstract

Sudden Infant Death Syndrome — United States, 1983-1994

http://www.cdc.gov/mmwr/preview/mmwrhtml/00043987.htm

RECALLS AND FIELD CORRECTIONS: BIOLOGICS — CLASS II PRODUCT Platelets. Recall #B-441-2. CODE Unit #90028. MANUFACTURER Memorial Blood Center of Minneapolis, Minneapolis, Minnesota. RECALLED BY Manufacturer, by telephone June 1, 1992. Firm-initiated recall complete. DISTRIBUTION Minnesota. QUANTITY 1 unit. REASON Blood product, which tested repeatedly reactive for the antibody to hepatitis B core antigen (anti-HBC), was distributed for transfusion.

http://www.fda.gov/bbs/topics/ENFORCE/ENF00175.html

Conflicts of Interest in Vaccine Policy Making
Majority Staff Report
Committee on Government Reform
U.S. House of Representatives
June 15, 2000

http://www.whale.to/v/staff.html

Reconstituted vaccines may become contaminated with staphylococcus and other

organisms from improper handling. Once this happens, a chemical called a toxin is

produced that may be deadly if injected.

http://www.who.int/vaccines-access/vacman/reconst/properhandlingeng.pdf

FLUMIST MEETING

http://www.fda.gov/ohrms/dockets/ac/02/transcripts/3912t1-01.pdf

Dangerous Prescription

http://www.pbs.org/wgbh/pages/frontline/shows/prescription/interviews/rich.html

http://www.pbs.org/wgbh/pages/frontline/shows/prescription/

Typing of human enteroviruses by partial sequencing of VP1.


http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=99221739

Calling the Shots:

Immunization Finance Policies and Practices (2000)
Institute of Medicine

WOW, this site compares vaccines used

1985 vs. 2000 vs. what they expect to be in use by

2020

http://books.nap.edu/books/0309070295/html/58.html#pagetop

History of the vaccine schedule:

http://www.chop.edu/consumer/jsp/division/generic.jsp?id=75700

Increased levels of active pertussis toxin may aid a pertussis vaccine to pass the mouse body weight gain test.

(my son failed this test)

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=7811458&dopt=Abstract

TB STATS, see how it’s declined without widespread vaccination. This may answer the question, what will happen if we stop vaccinating…

http://www.cdc.gov/nchstp/tb/surv/surv2001/pdf/T6and7.pdf

FAST STATS:

http://www.cdc.gov/nchs/fastats/Default.htm

Death after vaccine, unable to explain cause

http://www.emea.eu.int/pdfs/human/press/pus/851903en.pdf

Rotavirus Vaccine (they forgot to mention the 1-3 deaths that occurred after vaccination)

http://216.239.57.104/search?q=cache:YG88MnuIVZEJ:www.eurosurveillance.org/ew/2001/rtf/010301.rtf+rotavirus+mild&hl=en&ie=UTF-8

Weighing the risks and benefits of vaccination.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Retrieve&list_uids=9890055&dopt=Abstract

Information obtained via the Freedom of Information Act, watch how they discuss the adverse events related to the Rotashield vaccine, and basically decide to let more children be damaged while they decide if they should pull it off the market. Some appear quite concerned, but the end result is to let more children get hurt before they stop the madness…

http://www.aapsonline.org/testimony/cdcfoia.htm

Personal Statements:

Told to me in a phone conversation with Dr HH Fudenberg , (immunologist with over 45 years in the field, has had over 800 papers published in medical journals)

"I have no doubts the vaccine hurt your child. I have been warning them for years about the mecury and aluminum in vaccines. You should sue the dr that gave your son the Hep B vaccine."

Statement from a mom who had come to a vaccine debate board while pregnant and happened upon the vaccine controversy…

Thank you all for the information.

Base:

"http://boards.parentsplace.com/messages/get/ppvaccinedebate6.html"
Re: "http://boards.parentsplace.com/messages/get/ppvaccinedebate6/16.html"
Date: 1999, Dec 16
From: ivanat@ivillage.com

I stumbled across this board only shortly before the birth of my first child. I had already

filled in all the forms provided for me by care workers in order to facilitate our government’s ‘immunisation allowance’. I certainly wasn’t looking for either an argument or a support group. I had hitherto NEVER thought about the safety of vaccines. (this despite my own adverse or indifferent reactions to them)

Without trying to be dramatic about it, the doubt that began to form in my mind after reading some of the links you’ve all posted caused both my husband and I considerable angst! We read all your posts, we followed all the links, all the time resolved not to make any decisions based on purely political or emotional reasons. Difficult with some of those case studies in particular.

I even annoyed some of my relatives working in the medical professions for information. One in particular has been a research scientist in the field of infectious diseases for over 30 years. That was a bit of a coincidence and a jackpot. This is not only his specialty but an area that he has had opportunity to compare studies in over longer period of time. His opinion was invaluable, as were all of yours.

Anyhow, on the basis of all our research, we will not be vaccinating our girl (9 days old today!). Loveberry’s message is curt, but I felt the need to reply because we feel exactly the same way. So thank you all, both pro and anti vaccine posters.

Ivana.

 

About Uncle, Mum and little brothers and sisters.

Base:

"http://boards.parentsplace.com/messages/get/ppvaccinedebate6.html"
Re: "http://boards.parentsplace.com/messages/get/ppvaccinedebate6/16.html"
Re: "http://boards.parentsplace.com/messages/get/ppvaccinedebate6/16/1.html"

Re: "http://boards.parentsplace.com/messages/get/ppvaccinedebate6/16/1/1.html"

Date: 2000, Jan 23
From: ivanat@ivillage.com

To tell you more about my decision:

ABOUT UNCLE

Uncle’s special research involves infectious diseases and the treatment of them. He was particularly interested in the age group of 40yr and up as he believes they have established an informal link between their unusually high frequency of cancers and the vaccines they received as children. As a researcher, he reminded me first of all that his job is to be neither ‘for’ or ‘against’ any vaccine per say. Simply to be open minded. All the same, he did not allow his own children to be vaccinated as babies, waiting only until their teens. He was not only suspicious of the carcinogenic qualities of vaccines, but also frustrated by the high level of political involvement in all areas of research. He cited the length of time for any negative information relating to tobacco products to hit the media as an example. He felt very strongly about the involvement of politics and commerce in science. Another of his gripes had to do with the use of ‘Eastern Bloc’ populations as guinea pigs in new vaccine trials. Most of the vaccines that folk all the way from the balkans to the baltics were FORCED to have were never introduced in the west because of the number of adverse reactions.(everything from tooth decay to death).BTW, uncle lost some chidhood friends to vaccinations.

ABOUT MUM.

I brought this topic up with my mother, knowing that she had all six of us fully immunised. I expected her to nag me about it, but instead she admitted that she wished that she had never gone through with it. She says she felt bullied by doctors and nurses. I thought my own reactions had been a worry, but she revealed that the reason Damian and Ella had been to hospital as babies was due to their reaction to various shots. Ella had severe breathing difficulties and Damian had a bizarre virus involving ulceration of every area of mucous membrane in his body. Subsequent ear/nose/throat problems have persisted into adulthood. As a child, she also lost friends to vaccines. She was so scared of them herself that to avoid her shots, she took an abrasive pad and scratched up her arm to look as though she had already received them. BTW, she passed unscathed through every outbreak of disease in her town.

MY HUSBAND

My husband almost died from rubella complications as a child. He didn’t catch a wild strain though, he got his from a needle. A few weeks ago he got a tetanus shot after being bitten by a pregnant possum he was rescuing from the roadside. The doctor warned him that he might have a ‘bit of this and a bit of that’ after getting it, but didn’t tell him he’d collapse and be bedridden.

OUR DECISION

When we advised our docs nurses and midwives that we would not be giving our baby shots, all have implored us to seek specialist advice. We did. I shared my reservations with all of them; they were in the links you all provided (some dismissed them simply as being American propoganda) and in both our families’ medical histories. (that was more difficult to dismiss). Because we had every reason to believe that our daughter would have a similiar disposition, one doc. gave us the name of a male nurse (from a trad. medical background) who runs a naturopathic store in the city. Apparently he customises naturopathic treatments for those sensitive to vaccinations. We have an appointment in about a fortnight; I’ll let you know how it goes with him.

AFTER all this, I still realise that although we may have a long way to go in understanding the immune system, such endeavours as immunisation programmes had the best of intentions in their beginnings.

I also realise that even though my own family seems to have had a rough ride with shots, there must be many more out there who have nothing to write home about.

******************************************************************************************************************

You can get a good idea of how vaccines are handled in general by watching these four short parts of this video. It’s really appalling the way they use our children as guinea pigs…

This

is the Norwegian/New Zealand documentary on the Meningitis B vaccine.

http://tvnz.co.nz/view/page/413551/411801

*************************************************************************

Let’s look at vaccine schedules, then and now:

http://www.chop.edu/consumer/jsp/division/generic.jsp?id=75700

Vaccine Schedule

In the early 1950s, there were four vaccines: diphtheria, tetanus, pertussis and smallpox. Because three of these vaccines were combined into a single shot (DTP), children received five shots by the time they were 2 years old and not more than one shot at a single visit.

By the mid-1980s, there were seven vaccines: diphtheria, tetanus, pertussis, measles, mumps, rubella and polio. Because six of these vaccines were combined into two shots (DTP and MMR), and one, the polio vaccine, was given by mouth, children still received five shots by the time they were 2 years old and not more than one shot at a single visit.

Since the mid-1980s, many vaccines have been added to the schedule. Hib vaccine was added in the late-1980s. In the 1990s, hepatitis B and varicella vaccines were added and the polio vaccine shot (IPV) replaced the oral polio vaccine (OPV). In the year 2000, the pneumococcal vaccine was added. Now, children could receive as many as 20 shots by 2 years of age and five shots in a single visit!

(Dec of 2002, a 5 in 1 combo shot was licensed, Pediarix. Should a child have a reaction, it will be virtually impossible to determine which of the 5 were the cause.)

And more vaccines are to come. By 2005, it is likely that children will also be recommended to receive a meningococcal vaccine, the influenza vaccine and the hepatitis A vaccine, all given as shots.

******************************************************************

The following information has been provided by Tracy who is a big help to those looking for more information, I have edited some of it with her permission due to some of the links were personal and I didn’t want to include them on this public board:

The “other” vax information

Updated: October 6, 2005

Please note that as of now, Oct. 2005 I have once again updated this cheat sheet.

The other vax list:

FIRST OFF

If you are reading this list for the first time you may feel a bit overwhelmed. Take a deep breath and know this: You do not have to follow the doctor’s schedule for vaccinating your baby. You are well within your rights to delay until you make whatever decision makes you comfortable. This is your child, and your child deserves a well-educated decision, which can only be achieved by viewing all sides of an issue then choosing the path that is best for your child.

BACKGROUND

I decided to put together a list of links and books for those people who periodically ask me for vax information. When I say vax information I mean the “other” vax information.

There is one general vax assumption out there which pulsates like a drum beat….it says, “JUST DO IT.” I don’t need to support that message, there are plenty of ways one can get that information it’s just about anywhere….

I’ve compiled this list for those people who are questioning vaxing and the possible long term effects of it….. (we are a growing lot, by the way). Anyway, here are the links I learned about from friends, from my own researching, and from (a forum) of likeminded moms.

HARD NUMBERS

For me, I think the first place to begin is with hard numbers–Just how many cases of all these vax-diseases do we get here in the united states? (by the way, if you are out of the us I recommend you search your country’s online stats)

This is one of the hardest to find pages at the cdc… the way that I actually found this page was by accident. I had called the CDC to find out about hib cases and I got a doctor and he sent me to this page…

http://www.cdc.gov/mmwr/mmwr_wk.html

if you download the current issue it gives you the most uptodate stat that the cdc has on the reportable diseases by the way, the stats are at the end of the document. Anyway, I would start there first.

But just to give you an idea:
Here are the hard numbers for 2004. This is what I found for the last week of the year….. this is the total amount of cases reported to the CDC for 2004…..

Total reported cases to the cdc:

Disease Cases

Diptheria 0
Measles 37
Mumps 236
Rubella 12
Congenital rubella 0
Tetanus 26
Hib (under 5)
Sero b-16
Non sero b-114
Unknown b-156

Out of a population of 295 million people in the united states!!

If you check it now, you will see the number of cases for the year as of now (well to be specific as of last Friday. They update the list on Fridays or weekends-from what I can tell).

Remember it is a cumulative list… it is not that many cases per week. It’s the year to date.

I will say that critics of the CDC will say that the numbers don’t reflect all the cases since sometimes the cases are so mild they don’t even get reported or people don’t even go to the doctors because the symptoms are so manageable.

also….if you want to know how many people died of a disease–go to this link. plug in the disease.

http://wonder.cdc.gov/mortICD9J.html

you will be shocked by how small a number it is.

HARD NUMBERS ONE MORE TIME

Can we just go back to the topic of “hard numbers” …one more time…..

One of the smartest things a friend of mine who doesn’t vax said over and over again when I started to question vaxing (before my son was born) “start to figure out what your child is really at risk of getting.” And then weigh the risks of the vax to the real risks of getting the disease.

For example:
I live in a county with ten million people. Ten million people, that’s a lot. The last figures available online from the county health department were for 1999. That year there was one (1) case of measles reported. It was in a 44 year old woman.

There were also 250 cases of pertussis, (whooping cough) 250 out of 10 million is not much of a stat and then when I looked closer at the records I saw that of the 250 people, a certain percentage were children and of those children most had been vaxed for the disease. Only two children of the 250 were not vaxed and they were in a poor neighborhood with poor nutrition and possibly weakened immunity…Again in a county of ten million.

Also, periodically there are reports that come out stating that a city is experiencing an “epidemic” of pertussis. But what the article doesn’t always say is the number of pertussis cases that make an epidemic and of those cases many are in vaxed or partially vaxed children. There is an assumption made that it is always non vaxed children who get pertussis or are responsible for the rise of the disease. I hate that assumption and I really hate reporters who don’t do their homework.

I actually wonder if my own pediatrician knows those numbers… he probably does not…because that is the kind of research only parents who question have the dedication to find out….

More stats to consider

Polio has been eradicated in the western hemisphere and western Europe. As of 2003 there were around 700 cases of polio world wide and they were primarily in hot spots in India, Pakistan and sub Sahara Africa.

http://www.who.int/features/2004/polio/en/#

And then there is the data on vaccine injuries…kept by US dept of health. Basically a summery of the most dangerous vaxes…here is a link that contains that link plus more:

http://www.thememoryhole.org/health…us_vaccines.htm

MORE LINKS ON VAX

Then these links are valuable for information about vaxes and vax damages and other associations with vaccines. I know that some of these websites rub some people wrong…for a variety of reasons. And sure some of them can bug even me…but I feel like I should offer them up just for you to check out.

www.mercola.com

www.909shot.com

http://home.san.rr.com/via/

www.vaccinationdebate.com

http://www.vaccineinfo.net/

http://www.vaclib.org./

http://www.whale.to/vaccines/mendelsohn.html

http://www.whale.to/v/mend.html

more on vax ingredients

http://www.momtoanangel.net/ingred.htm
http://www.rense.com/general32/thru.htm

http://befreetech.com/vaccine_poisons.htm

http://www.justeatanapple.com/vaccination.html

Here is Sheri Nakken’s site…her site is loaded with info.

http://www.nccn.net/~wwithin/vaccine.htm

This organization is not necessarily where you go for vax information, but this is an institute that is passionately working on autism and helping parents and released the report last year about the epidemic proportion of autism in California. Caveat: the man who started this organization, his son developed autism after the MMR and he has been very vocal about such.

http://mindinstitute.ucdmc.ucdavis.edu/

INSERTS

A doctor is suppose to give you the inserts whenever they give your child a shot….I must say, from what I understand (since I passed on shots) that usually for some reason doesn’t happen….
Anyway, here is a link to those inserts

http://www.vaclib.org/chapter/inserts.htm

STATE STUFF

VACCINE EXEMPTIONS BY STATE:

http://members.tripod.com/suschi-ivil/vaccine_exemption_info/id1.html

WHAT EXEMPTIONS CAN I USE IN MY STATE FOR MY NON VAX CHILD TO GO TO SCHOOL?

http://www.909shot.com/state-site/state-exemptions.htm

and here is an example of exemption document you can offer your doctor if they want you to sign something.

http://www.vaclib.org/legal/refuselt.htm

any legal concerns?

http://www.vaccineexemption.org/

MORE DISCUSSION THREADS:

topic: Timeline of Thimerosal Controversy
(note–from Motherjones)

http://www.motherjones.com/news/fea…p_timeline.html

CANADA

Here is a canada link that might be helpful for those in canada

http://64.41.99.118/vran/legal/legal.htm

BOOKS TO READ

Get thy butt to Amazon

And finally here are books with the amazon.com links, which are very, very and very important to know about…read, study etc…. I started with Nuestadder’s book but I encourage you to check out the amazon links and see where you want to start.. (note: I provided the links to amazon..

· The Vaccine Guide: Making an Informed Choice by Randall Neustaedter, Randall the Immunization Decision Neusdaedter (Paperback)

http://www.amazon.com/exec/obidos/t…=books&n=507846

· How to Raise a Healthy Child in Spite of Your Doctor by Robert S. Mendelsohn (Paperback)

http://www.amazon.com/exec/obidos/t…=glance&s=books

· Confessions of a Medical Heretic by Robert S. Mendelsohn (Paperback)

http://www.amazon.com/exec/obidos/t…g=UTF8&v=glance

· A Shot in the Dark: Why the P in the Dpt Vaccination May Be Hazardous to Your Child’s Health by Harris L. Coulter, Barbara Loe Fisher (Paperback)

http://www.amazon.com/exec/obidos/t…=glance&s=books

· Vaccines: Are They Really Safe and Effective by Neil Z. Miller, et al (Paperback)

http://www.amazon.com/exec/obidos/t…=glance&s=books

Jamie Murphy. What Every Parent Should know about Childhood Immunization

http://www.amazon.com/exec/obidos/A…9894397-2579829

· The Immunization Resource Guide : Where to Find Answers to All Your Questions about Childhood Vaccinations by Diane Rozario (Paperback)

http://www.amazon.com/exec/obidos/t…=glance&s=books

· What Your Doctor May Not Tell You About Children’s Vaccinations by Stephanie Cave, Deborah Mitchell (Contributor) (Paperback)

http://www.amazon.com/exec/obidos/t…g=UTF8&v=glance

· Smart Medicine for a Healthier Child: A Practical A-To-Z Reference to Natural and Conventional Treatments for Infants and Children by Janet Zand, et al (Paperback)
· I should say, this book is pro-vax..which I am not thrilled about…but the other stuff is very, very helpful)

http://www.amazon.com/exec/obidos/t…=glance&s=books

· Vaccinations: A Thoughtful Parent’s Guide: How to Make Safe, Sensible Decisions about the Risks, Benefits, and Alternatives by Aviva Jill Romm (Paperback)

http://www.amazon.com/exec/obidos/A…9894397-2579829

· The Sanctity of Human Blood: Vaccination Is Not Immunization – Sixth Edition – 2003 — Tim O’Shea; Paperback

http://www.amazon.com/exec/obidos/t…=glance&s=books

· Naturally Healthy Babies & Children: A Commonsense Guide to Herbal Remedies by Aviva Jill Romm, William Sears (Paperback)

http://www.amazon.com/exec/obidos/t…=glance&s=books

IN CLOSING

And finally, this really should be stated over and over again….

NO ONE HAS TO FOLLOW ANY DOCTOR’S RULES FOR VAXING. MEANING YOU DON’T HAVE TO FOLLOW THE DOCTOR’S SCHEDULE. YOU MAKE YOUR OWN. IF YOU WANT TO DELAY VAXING UNTIL YOU’VE DONE YOUR RESEARCH AND YOU FEEL CONFIDENT ABOUT THAT DECISION THEN THAT IS WHAT YOU SHOULD DO. DELAY UNTIL YOU ARE SURE OF WHAT YOU ARE DOING. AND NOT ONE MINUTE BEFORE. REMEMBER IT IS YOUR CHILD. NOT YOUR DOCTOR’S.

good luck and happy researching!

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Also wanted to add this personal story from a mother who didn’t get her child any vaccines until he was four years old, and now regrets it.  Her story is posted with her permission:

Sharing my story

My mom, who has been the biggest influence in my life, never vaccinated me and my sister, because her sister and cousin both got Polio from their vaccinations. In fact, her cousin spent the first several years of his life in an "iron lung", and the rest in a wheelchair. And she remembers getting violently ill after her vaccs. So I grew up knowing vaccinations weren’t okay, but I never did any research on them myself.

When I had my son I decided I wouldn’t vaccinate him, just like my mom did with me, but still did no research. In the hospital when I declined having him vaccinated, about 10 nurses(most I had never seen before) filled my room to convince me that I MUST vaccinate my son. I stood my ground and took my baby home unvaccinated. I only took my son to the doctor once because I thought his imbilical cord stub might be bleeding, but that’s it, no WB appts.

Fast forward 4 years- My son fell off a backyard metal toy and cut his gums so bad they had to pull a tooth. My mom said "he should get a Tetnus shot, so he doesn’t develop lockjaw", and I, not having done any research myself , said "okay". Took him to the clinic, told them what happened and said I wanted a Tetnus shot for him. The Physician Assistant tells me,"Oh, well we can’t give him just a Tetnus shot, it has to be the Diptheria, Pertussis, Tetnus shot. That’s the only way the vaccine comes." Now to be honest, in my heart of hearts, I felt to grab my son and run out the door. I just new it wasn’t right, but thinking he "needed" the Tetnus shot, I said "okay". My son has never been the same since. That same evening after the shot my son developed dark circles under his eyes, and the worst putrid breath. At first I thought it was from the injury and stress, but the injury healed and still the dark circles and putrid breath remained. He started catching everything that came around, and developed problems with constipation. He was tired all the time, and sometimes just felt so miserable he would lay on the floor and cry and whimper. (Everytime I think about it, it makes me want to scream ! How could I let that happen to him! )

My son’s 12 now, and through healthy food and supplements he has made some recovery. But now that I found this forum and read up about the Sodium Ascorbate, I’m going to start him on a regiment of that. I want my healthy, happy, bright eyed boy back, and I am determined to find the way to undo what I allowed to happen to him.

Just wanted to share my story. And say thank you to all of you who have shared your knowledge here.

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Decreases In Disease Risks

Today, vaccine-preventable diseases are at or near record lows. By virtue of their absence, these diseases are no longer reminders of the benefits of vaccination. At the same time, approximately 15,000 cases of adverse events following vaccination are reported in the United States each year (these include both true adverse reactions and events that occur coincidentally after vaccination). This number exceeds the current reported incidence of vaccine-preventable childhood diseases. As a result, parents and providers in the United States are more likely to know someone who has experienced an adverse event following immunization than they are to know someone who has experienced a reportable vaccine-preventable disease. Thus, the success of vaccination has led to increased public attention on health risks associated with vaccines.

http://www.cdc.gov/nip/publications/pink/safety.pdf

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In the United States, The National Childhood Vaccine Injury Act of 1986 established a Committee from the Institute of Medicine (IOM) to review the adverse consequences of childhood vaccines.

This group found severe limits in the knowledge and research capability on vaccine safety.

Of the 76 vaccine adverse events they reviewed for causal relation, 50 (66%) had no or inadequate research.

Specifically, the IOM Committees identified the following limitation’s:

1) Inadequate understanding of biologic mechanisms underlying adverse events;

2) Insufficient or inconsistent information from case reports and case series;

3) Inadequate size or length of follow-up of many population-based epidemiologic studies;

4) Limitations of existing surveillance systems to provide persuasive evidence of causation and

5) Few experimental studies published relative to the total number of epidemiologic studies published.13,14

http://www.cdc.gov/nip/vacsafe/research/peds.htm

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